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Roles of PLODs in Collagen Synthesis and Cancer Progression

Collagen is the major component of extracellular matrix. Collagen cross-link and deposition depend on lysyl hydroxylation, which is catalyzed by procollagen-lysine, 2-oxoglutarate 5-dioxygenase (PLOD). Aberrant lysyl hydroxylation and collagen cross-link contributes to the progression of many collag...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Qi, Yifei, Xu, Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031748/
https://ncbi.nlm.nih.gov/pubmed/30003082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00066
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