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Roles of PLODs in Collagen Synthesis and Cancer Progression
Collagen is the major component of extracellular matrix. Collagen cross-link and deposition depend on lysyl hydroxylation, which is catalyzed by procollagen-lysine, 2-oxoglutarate 5-dioxygenase (PLOD). Aberrant lysyl hydroxylation and collagen cross-link contributes to the progression of many collag...
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| Published in: | Front Cell Dev Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031748/ https://ncbi.nlm.nih.gov/pubmed/30003082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00066 |
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