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The Collagen-Modifying Enzyme PLOD2 Is Induced and Required during L1-Mediated Colon Cancer Progression

The overactivation of Wnt/β-catenin signaling is a hallmark of colorectal cancer (CRC) development. We identified the cell adhesion molecule L1CAM (L1) as a target of β-catenin-TCF transactivation in CRC cells. The overexpression of L1 in CRC cells confers enhanced proliferation, motility, tumorigen...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cheriyamundath, Sanith, Kumar, Anmol, Gavert, Nancy, Brabletz, Thomas, Ben-Ze’ev, Avri
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038063/
https://ncbi.nlm.nih.gov/pubmed/33805564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073552
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