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Nuclear factor-κB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells
Hyperactivation of β-catenin–T-cell-factor (TCF)-regulated gene transcription is a hallmark of colorectal cancer (CRC). The cell-neural adhesion molecule L1CAM (hereafter referred to as L1) is a target of β-catenin–TCF, exclusively expressed at the CRC invasive front in humans. L1 overexpression in...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4481617/ https://ncbi.nlm.nih.gov/pubmed/20501702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.069542 |
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