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Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis

Hyperactive Wnt signaling is a common feature in human colorectal cancer (CRC) cells. A central question is the identification and role of Wnt/β-catenin target genes in CRC and their relationship to genes enriched in colonic stem cells, since Lgr5+ intestinal stem cells were suggested to be the cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Shapiro, Beny, Tocci, Piera, Haase, Gal, Gavert, Nancy, Ben-Ze'ev, Avri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741460/
https://ncbi.nlm.nih.gov/pubmed/26399194
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