Wnt signaling in cancer stem cells and colon cancer metastasis [version 1; referees: 3 approved]

Overactivation of Wnt signaling is a hallmark of colorectal cancer (CRC). The Wnt pathway is a key regulator of both the early and the later, more invasive, stages of CRC development. In the normal intestine and colon, Wnt signaling controls the homeostasis of intestinal stem cells (ISCs) that fuel,...

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Detalhes bibliográficos
Main Authors: Sayon Basu, Gal Haase, Avri Ben-Ze'ev
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Ltd 2016-04-01
Colecção:F1000Research
Assuntos:
Cell Growth & Division
Cell Signaling
Developmental Molecular Mechanisms
Gastrointestinal Cancers
Gastrointestinal Physiology
Medical Genetics
Stem Cells & Regeneration
Acesso em linha:http://f1000research.com/articles/5-699/v1
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