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Mis16 Switches Function from a Histone H4 Chaperone to a CENP-A(Cnp1)-Specific Assembly Factor through Eic1 Interaction

The Mis18 complex, composed of Mis16, Eic1, and Mis18 in fission yeast, selectively deposits the centromere-specific histone H3 variant, CENP-A(Cnp1), at centromeres. How the intact Mis18 holo-complex oligomerizes and how Mis16, a well-known ubiquitous histone H4 chaperone, plays a centromere-specif...

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Publicado en:Structure
Autores principales: An, Sojin, Koldewey, Philipp, Chik, Jennifer, Subramanian, Lakxmi, Cho, Uhn-Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031460/
https://ncbi.nlm.nih.gov/pubmed/29804820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.04.012
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