Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly

CENP-A chromatin forms the foundation for kinetochore assembly. Replication-independent incorporation of CENP-A at centromeres depends on its chaperone HJURP(Scm3), and Mis18 in vertebrates and fission yeast. The recruitment of Mis18 and HJURP(Scm3) to centromeres is cell cycle regulated. Vertebrate...

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Bibliographic Details
Main Authors: Subramanian, Lakxmi, Toda, Nicholas R. T., Rappsilber, Juri, Allshire, Robin C.
Format: Artigo
Language:Inglês
Published: The Royal Society 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043117/
https://ncbi.nlm.nih.gov/pubmed/24789708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140043
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