Centromere localization and function of Mis18 requires Yippee‐like domain‐mediated oligomerization

Mis18 is a key regulator responsible for the centromere localization of the CENP‐A chaperone Scm3 in Schizosaccharomyces pombe and HJURP in humans, which establishes CENP‐A chromatin that defines centromeres. The molecular and structural determinants of Mis18 centromere targeting remain elusive. Her...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Subramanian, Lakxmi, Medina‐Pritchard, Bethan, Barton, Rachael, Spiller, Frances, Kulasegaran‐Shylini, Raghavendran, Radaviciute, Guoda, Allshire, Robin C, Arockia Jeyaprakash, A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818781/
https://ncbi.nlm.nih.gov/pubmed/26921242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541520
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