Reconstituting Drosophila Centromere Identity in Human Cells

The centromere is an essential chromosomal region required for accurate chromosome segregation. Most eukaryotic centromeres are defined epigenetically by the histone H3 variant, centromere protein (CENP)-A, yet how its self-propagation is achieved remains poorly understood. Here, we develop a hetero...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Roure, Virginie, Medina-Pritchard, Bethan, Lazou, Vasiliki, Rago, Luciano, Anselm, Eduard, Venegas, Daniela, Jeyaprakash, A. Arockia, Heun, Patrick
Format: Artigo
Language:Inglês
Published: Cell Press 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900781/
https://ncbi.nlm.nih.gov/pubmed/31597104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.067
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