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A BK channel–mediated feedback pathway links single-synapse activity with action potential sharpening in repetitive firing
Action potential shape is a major determinant of synaptic transmission, and mechanisms of spike tuning are therefore of key functional significance. We demonstrate that synaptic activity itself modulates future spikes in the same neuron via a rapid feedback pathway. Using Ca(2+) imaging and targeted...
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| Publicat a: | Sci Adv |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Association for the Advancement of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031373/ https://ncbi.nlm.nih.gov/pubmed/29978045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat1357 |
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