Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) plays an important role in the progression of renal interstitial fibrosis, which finally leads to renal failure. Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with unilateral...

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Veröffentlicht in:BMC Complement Altern Med
Hauptverfasser: He, Wei-ming, Yin, Jia-qi, Cheng, Xu-dong, Lu, Xun, Ni, Li, Xi, Yi, Yin, Gui-dong, Lu, Guo-yuan, Sun, Wei, Wei, Ming-gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031099/
https://ncbi.nlm.nih.gov/pubmed/29973206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-018-2265-y
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