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Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) plays an important role in the progression of renal interstitial fibrosis, which finally leads to renal failure. Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with unilateral...
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| Publié dans: | BMC Complement Altern Med |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031099/ https://ncbi.nlm.nih.gov/pubmed/29973206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-018-2265-y |
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