Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

The early growth response- (Egr-) 1 has been found to play a key role in organ fibrosis. Metformin has been shown to be effective in attenuating renal tubular epithelial-to-mesenchymal transition (EMT), which is involved in renal fibrosis. However, it is unknown whether metformin improves EMT via in...

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Vydáno v:J Diabetes Res
Hlavní autoři: Guan, Meiping, Li, Wenqi, Xu, Lingling, Zeng, Yanmei, Wang, Dan, Zheng, Zongji, Lyv, Fuping, Xue, Yaoming
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040246/
https://ncbi.nlm.nih.gov/pubmed/30050950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1031367
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