GDSCTools for mining pharmacogenomic interactions in cancer

MOTIVATION: Large pharmacogenomic screenings integrate heterogeneous cancer genomic datasets as well as anti-cancer drug responses on thousand human cancer cell lines. Mining this data to identify new therapies for cancer sub-populations would benefit from common data structures, modular computation...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Cokelaer, Thomas, Chen, Elisabeth, Iorio, Francesco, Menden, Michael P, Lightfoot, Howard, Saez-Rodriguez, Julio, Garnett, Mathew J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Applications Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031019/
https://ncbi.nlm.nih.gov/pubmed/29186349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx744
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