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Transcriptional data: a new gateway to drug repositioning?
Recent advances in computational biology suggest that any perturbation to the transcriptional programme of the cell can be summarised by a proper ‘signature’: a set of genes combined with a pattern of expression. Therefore, it should be possible to generate proxies of clinicopathological phenotypes...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625109/ https://ncbi.nlm.nih.gov/pubmed/22897878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2012.07.014 |
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