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Optimality of the genetic code with respect to protein stability and amino-acid frequencies

BACKGROUND: The genetic code is known to be efficient in limiting the effect of mistranslation errors. A misread codon often codes for the same amino acid or one with similar biochemical properties, so the structure and function of the coded protein remain relatively unaltered. Previous studies have...

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Autors principals: Gilis, Dimitri, Massar, Serge, Cerf, Nicolas J, Rooman, Marianne
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC60310/
https://ncbi.nlm.nih.gov/pubmed/11737948
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