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Protective role of the lipid phosphatase Fig4 in the adult nervous system
The signaling lipid phosphatidylinositol 3,5-bisphosphate, PI(3,5)P(2), functions in vesicular trafficking through the endo-lysosomal compartment. Cellular levels of PI(3,5)P(2) are regulated by an enzyme complex comprised of the kinase PIKFYVE, the phosphatase FIG4, and the scaffold protein VAC14....
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030899/ https://ncbi.nlm.nih.gov/pubmed/29688489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy145 |
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