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Refining Protein Penetration into the Lipid Bilayer Using Fluorescence Quenching and Molecular Dynamics Simulations: The Case of Diphtheria Toxin Translocation Domain

Dynamic disorder of the lipid bilayer presents a challenge for establishing structure-function relationships in membraneous systems. The resulting structural heterogeneity is especially evident for peripheral and spontaneously inserting membrane proteins, which are not constrained by the well-define...

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Bibliographic Details
Published in:J Membr Biol
Main Authors: Kyrychenko, Alexander, Lim, Nathan M., Vasquez-Montes, Victor, Rodnin, Mykola V., Freites, J. Alfredo, Nguyen, Linh P., Tobias, Douglas J., Mobley, David L., Ladokhin, Alexey S.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030514/
https://ncbi.nlm.nih.gov/pubmed/29550876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-018-0030-2
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