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Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate
Type-2 immunity is regulated by two distinct CD4+ T cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. T helper type-2 (Th2) cells orchestrate type-2 inflammation in peripheral tissues, such as the lung and intestine. Given the importance of Notc...
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| Veröffentlicht in: | Mucosal Immunol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030499/ https://ncbi.nlm.nih.gov/pubmed/29467447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0012-9 |
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