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Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate

Type-2 immunity is regulated by two distinct CD4+ T cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. T helper type-2 (Th2) cells orchestrate type-2 inflammation in peripheral tissues, such as the lung and intestine. Given the importance of Notc...

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Bibliografiske detaljer
Udgivet i:Mucosal Immunol
Main Authors: Dell'Aringa, Mark, Reinhardt, R. Lee
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030499/
https://ncbi.nlm.nih.gov/pubmed/29467447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0012-9
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