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Strength of tonic T cell receptor signaling instructs T follicular helper fate decisions
T follicular helper (Tfh) cells are critical in adaptive immune responses to pathogens and vaccines; however, what drives initiation of their developmental program remains unclear. Studies suggest a T cell antigen receptor (TCR)-dependent mechanism may be responsible for the earliest Tfh-fate decisi...
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| Publicat a: | Nat Immunol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7578106/ https://ncbi.nlm.nih.gov/pubmed/32989327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0781-7 |
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