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Tonic TCR signaling inversely regulates the basal metabolism of CD4+ T Cells

The contribution of self-peptide-MHC signaling in CD4+ T cells to metabolic programming has not been definitively established. Here, we employed LLO118 and LLO56, two TCRtg CD4+ T cells that recognize the same Listeria epitope. We previously have shown that LLO56 T cells are highly self-reactive and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunohorizons
Egile Nagusiak: Milam, Ashley A. Viehmann, Bartleson, Juliet M., Buck, Michael D., Chang, Chih-Hao, Sergushichev, Alexey, Donermeyer, David L., Lam, Wing Y., Pearce, Erika L., Artyomov, Maxim N., Allen, Paul M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500861/
https://ncbi.nlm.nih.gov/pubmed/32769180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.2000055
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