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Tumor-Specific Mitochondrial DNA Variants Are Rarely Detected in Cell-Free DNA()()
The use of blood-circulating cell-free DNA (cfDNA) as a “liquid biopsy” in oncology is being explored for its potential as a cancer biomarker. Mitochondria contain their own circular genomic entity (mitochondrial DNA, mtDNA), up to even thousands of copies per cell. The mutation rate of mtDNA is sev...
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| Publicado no: | Neoplasia |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030393/ https://ncbi.nlm.nih.gov/pubmed/29842994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.05.003 |
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