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Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model

Recent regulatory T cell (Treg) based clinical trials support their therapeutic potential in transplantation and auto-inflammatory diseases. However, large numbers of Treg are needed to accomplish therapeutic efficacy. Local injection at the site of inflammation (targeted delivery) may lower the num...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Landman, Sija, de Oliveira, Vivian L., van Erp, Piet E. J., Fasse, Esther, Bauland, Stijn C. G., Joosten, Irma, Koenen, Hans J. P. M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030170/
https://ncbi.nlm.nih.gov/pubmed/29968819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28346-5
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