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Detecting somatic mutations in normal cells

Somatic mutations have been studied extensively in the context of cancer. Recent studies have demonstrated that high-throughput sequencing data can be used to detect somatic mutations in non-tumor cells. Analysis of such mutations allows us to better understand the mutational processes in normal cel...

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Publicat a:Trends Genet
Autors principals: Dou, Yanmei, Gold, Heather D., Luquette, Lovelace J., Park, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029698/
https://ncbi.nlm.nih.gov/pubmed/29731376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2018.04.003
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