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p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionarily conserved and widespread histone mark like lysine acetylation (Kac). Here we report that p300 functions as a lysine 2-hyroxyisobutyryltransferase to regulate glycolysis in response to nutritional cues. We discovered that p300 differentially...
में बचाया:
| में प्रकाशित: | Mol Cell |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6029451/ https://ncbi.nlm.nih.gov/pubmed/29775581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.011 |
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