p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis

Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionarily conserved and widespread histone mark like lysine acetylation (Kac). Here we report that p300 functions as a lysine 2-hyroxyisobutyryltransferase to regulate glycolysis in response to nutritional cues. We discovered that p300 differentially...

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Publicat a:Mol Cell
Autors principals: Huang, He, Tang, Shuang, Ji, Ming, Tang, Zhanyun, Shimada, Miho, Liu, Xiaojing, Qi, Shankang, Locasale, Jason W., Roeder, Robert G., Zhao, Yingming, Li, Xiaoling
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029451/
https://ncbi.nlm.nih.gov/pubmed/29775581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.011
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