A quantitative map of human Condensins provides new insights into mitotic chromosome architecture

The two Condensin complexes in human cells are essential for mitotic chromosome structure. We used homozygous genome editing to fluorescently tag Condensin I and II subunits and mapped their absolute abundance, spacing, and dynamic localization during mitosis by fluorescence correlation spectroscopy...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Walther, Nike, Hossain, M. Julius, Politi, Antonio Z., Koch, Birgit, Kueblbeck, Moritz, Ødegård-Fougner, Øyvind, Lampe, Marko, Ellenberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028534/
https://ncbi.nlm.nih.gov/pubmed/29632028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201801048
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