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A novel high-affinity inhibitor against the human ATP-sensitive Kir6.2 channel
The adenosine triphosphate (ATP)-sensitive (K(ATP)) channels in pancreatic β cells couple the blood glucose level to insulin secretion. K(ATP) channels in pancreatic β cells comprise the pore-forming Kir6.2 and the modulatory sulfonylurea receptor 1 (SUR1) subunits. Currently, there is no high-affin...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028498/ https://ncbi.nlm.nih.gov/pubmed/29844136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812017 |
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