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CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9
Cis -regulatory elements (CREs) play a pivotal role in spatiotemporal control of tissue-specific gene expression, yet the molecular composition of the vast majority of CREs in native chromatin remains unknown. In this unit, we describe the CRISPR affinity purification in situ of regulatory elements...
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| Publicado no: | Curr Protoc Mol Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028316/ https://ncbi.nlm.nih.gov/pubmed/29927077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.64 |
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