A model for postzygotic mosaicisms quantifies the allele fraction drift, mutation rate, and contribution to de novo mutations

Lignende værker

• Postzygotic single‐nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations
  af: Dou, Yanmei, et al.
  Udgivet: (2017)
• MosaicHunter: accurate detection of postzygotic single-nucleotide mosaicism through next-generation sequencing of unpaired, trio, and paired samples
  af: Huang, August Yue, et al.
  Udgivet: (2017)
• MosaicBase: A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals
  af: Yang, Xiaoxu, et al.
  Udgivet: (2020)
• Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs
  af: Huang, August Yue, et al.
  Udgivet: (2018)
• Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo” SCN1A Mutations in Children with Dravet Syndrome
  af: Xu, Xiaojing, et al.
  Udgivet: (2015)