Postzygotic single‐nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations

The roles and characteristics of postzygotic single‐nucleotide mosaicisms (pSNMs) in autism spectrum disorders (ASDs) remain unclear. In this study of the whole exomes of 2,361 families in the Simons Simplex Collection, we identified 1,248 putative pSNMs in children and 285 de novo SNPs in children...

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Bibliografiska uppgifter
I publikationen:Hum Mutat
Huvudupphovsmän: Dou, Yanmei, Yang, Xiaoxu, Li, Ziyi, Wang, Sheng, Zhang, Zheng, Ye, Adam Yongxin, Yan, Linlin, Yang, Changhong, Wu, Qixi, Li, Jiarui, Zhao, Boxun, Huang, August Yue, Wei, Liping
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518181/
https://ncbi.nlm.nih.gov/pubmed/28503910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23255
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