Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals

Postzygotic single-nucleotide mutations (pSNMs) have been studied in cancer and a few other overgrowth human disorders at whole-genome scale and found to play critical roles. However, in clinically unremarkable individuals, pSNMs have never been identified at whole-genome scale largely due to techni...

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Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Huang, August Y, Xu, Xiaojing, Ye, Adam Y, Wu, Qixi, Yan, Linlin, Zhao, Boxun, Yang, Xiaoxu, He, Yao, Wang, Sheng, Zhang, Zheng, Gu, Bowen, Zhao, Han-Qing, Wang, Meng, Gao, Hua, Gao, Ge, Zhang, Zhichao, Yang, Xiaoling, Wu, Xiru, Zhang, Yuehua, Wei, Liping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220156/
https://ncbi.nlm.nih.gov/pubmed/25312340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.131
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