Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains

Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism by which chromatin regulators contribute to ASD risk remains poorly understood....

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Zhao, Ying-Tao, Kwon, Deborah Y., Johnson, Brian S., Fasolino, Maria, Lamonica, Janine M., Kim, Yoon Jung, Zhao, Boxuan Simen, He, Chuan, Vahedi, Golnaz, Kim, Tae Hoon, Zhou, Zhaolan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028126/
https://ncbi.nlm.nih.gov/pubmed/29848492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233775.117
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