Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains

Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism by which chromatin regulators contribute to ASD risk remains poorly understood....

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Enregistré dans:
Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Zhao, Ying-Tao, Kwon, Deborah Y., Johnson, Brian S., Fasolino, Maria, Lamonica, Janine M., Kim, Yoon Jung, Zhao, Boxuan Simen, He, Chuan, Vahedi, Golnaz, Kim, Tae Hoon, Zhou, Zhaolan
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028126/
https://ncbi.nlm.nih.gov/pubmed/29848492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233775.117
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