Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains

Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism by which chromatin regulators contribute to ASD risk remains poorly understood....

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Vydáno v:Genome Res
Hlavní autoři: Zhao, Ying-Tao, Kwon, Deborah Y., Johnson, Brian S., Fasolino, Maria, Lamonica, Janine M., Kim, Yoon Jung, Zhao, Boxuan Simen, He, Chuan, Vahedi, Golnaz, Kim, Tae Hoon, Zhou, Zhaolan
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028126/
https://ncbi.nlm.nih.gov/pubmed/29848492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233775.117
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