Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing

N6-Methyladenine (m(6)dA) has been discovered as a novel form of DNA methylation prevalent in eukaryotes; however, methods for high-resolution mapping of m(6)dA events are still lacking. Single-molecule real-time (SMRT) sequencing has enabled the detection of m(6)dA events at single-nucleotide resol...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Zhu, Shijia, Beaulaurier, John, Deikus, Gintaras, Wu, Tao P., Strahl, Maya, Hao, Ziyang, Luo, Guanzheng, Gregory, James A., Chess, Andrew, He, Chuan, Xiao, Andrew, Sebra, Robert, Schadt, Eric E., Fang, Gang
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2018
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028124/
https://ncbi.nlm.nih.gov/pubmed/29764913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.231068.117
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