Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing

Although extensively studied in prokaryotes, the prevalence and significance of DNA N(6)-methyladenine (6mA or m(6)dA) in eukaryotes had been underappreciated until recent studies, which have demonstrated that 6mA regulates gene expression as a potential heritable mark. To interrogate 6mA sites at s...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Luo, Guan-Zheng, Wang, Fang, Weng, Xiaocheng, Chen, Kai, Hao, Ziyang, Yu, Miao, Deng, Xin, Liu, Jianzhao, He, Chuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835550/
https://ncbi.nlm.nih.gov/pubmed/27079427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11301
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