Targeting TWIST1 through loss of function inhibits tumorigenicity of human glioblastoma

TWIST1 (TW) is a bHLH transcription factor (TF) and master regulator of the epithelial‐to‐mesenchymal transition (EMT). In vitro, TW promotes mesenchymal change, invasion, and self‐renewal in glioblastoma (GBM) cells. However, the potential therapeutic relevance of TW has not been established throug...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Mikheev, Andrei M., Mikheeva, Svetlana A., Severs, Liza J., Funk, Cory C., Huang, Lei, McFaline‐Figueroa, José L., Schwensen, Jeanette, Trapnell, Cole, Price, Nathan D., Wong, Stephen, Rostomily, Robert C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026950/
https://ncbi.nlm.nih.gov/pubmed/29754406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12320
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