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Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase
Polyprotein processing has an important regulatory role in the life cycle of positive-strand RNA viruses. In the case of alphaviruses, sequential cleavage of the nonstructural polyprotein (ns-polyprotein) at three sites eventually yields four mature nonstructural proteins (nsPs) that continue workin...
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| Udgivet i: | J Virol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026757/ https://ncbi.nlm.nih.gov/pubmed/29695431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00151-18 |
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