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Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis

Semliki Forest virus (genus Alphavirus) is an important model for studying regulated nonstructural (ns) polyprotein processing. In this study, we evaluated the strictness of the previously outlined cleavage rules, accounting for the timing and outcome of each of three cleavages within the ns polypro...

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Detalhes bibliográficos
Main Authors: Lulla, Valeria, Karo-Astover, Liis, Rausalu, Kai, Merits, Andres, Lulla, Aleksei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754006/
https://ncbi.nlm.nih.gov/pubmed/23864614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01485-13
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