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Herpes Simplex Virus 2 Latency-Associated Transcript (LAT) Region Mutations Do Not Identify a Role for LAT-Associated MicroRNAs in Viral Reactivation in Guinea Pig Genital Models

Despite the long-standing observation that herpes simplex virus (HSV) latency-associated transcript (LAT) promoter deletion viruses show impaired recurrence phenotypes in relevant animal models, the mechanism by which these sequences exert this phenotypic effect is unknown. We constructed and evalua...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kawamura, Yoshiki, Bosch-Marce, Marta, Tang, Shuang, Patel, Amita, Krause, Philip R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026728/
https://ncbi.nlm.nih.gov/pubmed/29720520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00642-18
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