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Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs

The latency-associated transcript (LAT) is the only herpes simplex virus (HSV) gene product detectable in latently infected humans and animals. In this report, we show that a 624-bp deletion in the promoter of the HSV-2 LAT had no discernable effect on viral growth in tissue culture or in acute geni...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191851/
https://ncbi.nlm.nih.gov/pubmed/7807009
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