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Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer

In the United States alone one in five newly diagnosed cancers in men are prostate carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal transduction pathway are critical in PCa. After initial response to single drugs targeting these pathways resistance often emerges, indicati...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:NPJ Syst Biol Appl
Main Authors: Ebhardt, H. Alexander, Root, Alex, Liu, Yansheng, Gauthier, Nicholas Paul, Sander, Chris, Aebersold, Ruedi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026592/
https://ncbi.nlm.nih.gov/pubmed/29977602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0064-1
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