Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer

In the United States alone one in five newly diagnosed cancers in men are prostate carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal transduction pathway are critical in PCa. After initial response to single drugs targeting these pathways resistance often emerges, indicati...

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Detaylı Bibliyografya
Yayımlandı:NPJ Syst Biol Appl
Asıl Yazarlar: Ebhardt, H. Alexander, Root, Alex, Liu, Yansheng, Gauthier, Nicholas Paul, Sander, Chris, Aebersold, Ruedi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026592/
https://ncbi.nlm.nih.gov/pubmed/29977602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0064-1
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