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Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer

In the United States alone one in five newly diagnosed cancers in men are prostate carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal transduction pathway are critical in PCa. After initial response to single drugs targeting these pathways resistance often emerges, indicati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Syst Biol Appl
Hauptverfasser: Ebhardt, H. Alexander, Root, Alex, Liu, Yansheng, Gauthier, Nicholas Paul, Sander, Chris, Aebersold, Ruedi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026592/
https://ncbi.nlm.nih.gov/pubmed/29977602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0064-1
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