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The Proline Cycle As a Potential Cancer Therapy Target
Interest in how proline contributes to cancer biology is expanding because of the emerging role of a novel proline metabolic cycle in cancer cell survival, proliferation, and metastasis. Proline biosynthesis and degradation involve the shared intermediate Δ(1)-pyrroline-5-carboxylate (P5C), which fo...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026536/ https://ncbi.nlm.nih.gov/pubmed/29648801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00215 |
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