The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70

Epstein–Barr virus (EBV) can infect cells in latent and lytic period and cause serious disease. Epstein–Barr virus nuclear antigen 1 (EBNA1) is essential for the maintenance of the EBV DNA episome, replication and transcription. 2-phenylethynesulfonamide (PES) is a small molecular inhibitor of Heat...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Huan, Bu, Lang, Wang, Chao, Zhang, Yaqian, Zhou, Heng, Zhang, Xi, Guo, Wei, Long, Cong, Guo, Deyin, Sun, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026193/
https://ncbi.nlm.nih.gov/pubmed/29959331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0779-3
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