The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats

Chronic NP-1 administration reduces body weight and hepatic steatosis despite induction of tolerance in adiponectin gene transcription with respect to the acute actions of this drug. This study explored the hypothesis that NP-1 could exert these effects through mechanisms independent of adiponectin....

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Decara, Juan, Serrano, Antonia, Pavón, Francisco Javier, Rivera, Patricia, Arco, Rocio, Gavito, Ana, Vargas, Antonio, Navarro, Juan A., Tovar, Ruben, Lopez-Gambero, Antonio J., Martínez, Ana, Suárez, Juan, Rodríguez de Fonseca, Fernando, Baixeras, Elena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026175/
https://ncbi.nlm.nih.gov/pubmed/29959379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27871-7
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