Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin

Colistin remains one of the few antibiotics effective against multi-drug resistant (MDR) hospital pathogens, such as Klebsiella pneumoniae. Yet resistance to this last-line drug is rapidly increasing. Characterized mechanisms of col(R) in K. pneumoniae are largely due to chromosomal mutations in two...

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Pubblicato in:Sci Rep
Autori principali: Cain, Amy K., Boinett, Christine J., Barquist, Lars, Dordel, Janina, Fookes, Maria, Mayho, Matthew, Ellington, Matthew J., Goulding, David, Pickard, Derek, Wick, Ryan R., Holt, Kathryn E., Parkhill, Julian, Thomson, Nicholas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026146/
https://ncbi.nlm.nih.gov/pubmed/29959380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28199-y
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